Tong Zhou Selected Research

Death Domain Receptors

1/2020	Regulation of pancreatic cancer TRAIL resistance by protein O-GlcNAcylation.
1/2019	Cytoplasmic PARP-1 promotes pancreatic cancer tumorigenesis and resistance.
1/2017	Calmodulin Binding to Death Receptor 5-mediated Death-Inducing Signaling Complex in Breast Cancer Cells.
4/2014	Characterization of calmodulin-Fas death domain interaction: an integrated experimental and computational study.
9/2013	PARP-1 regulates resistance of pancreatic cancer to TRAIL therapy.
3/2011	The role of DDX3 in regulating Snail.
7/2009	Effect of TRA-8 anti-death receptor 5 antibody in combination with chemotherapy in an ex vivo human ovarian cancer model.
4/2008	Treatment of human colon cancer xenografts with TRA-8 anti-death receptor 5 antibody alone or in combination with CPT-11.
9/2006	Inducible resistance of tumor cells to tumor necrosis factor-related apoptosis-inducing ligand receptor 2-mediated apoptosis by generation of a blockade at the death domain function.
8/2006	TRAIL receptor-targeted therapy.

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Tong Zhou Research Topics

Disease

85	Neoplasms (Cancer) 10/2022 - 08/2002
27	Infections 01/2022 - 09/2002
26	Inflammation (Inflammations) 09/2022 - 07/2006
17	Neoplasm Metastasis (Metastasis) 01/2022 - 07/2003
17	Stomach Neoplasms (Stomach Cancer) 01/2022 - 07/2003
14	Fibrosis (Cirrhosis) 01/2021 - 06/2006
12	Lung Neoplasms (Lung Cancer) 01/2021 - 09/2005
11	Colorectal Neoplasms (Colorectal Cancer) 10/2021 - 04/2006
11	Breast Neoplasms (Breast Cancer) 01/2019 - 09/2003
11	Carcinogenesis 01/2019 - 12/2004
10	Pancreatic Neoplasms (Pancreatic Cancer) 01/2020 - 09/2007
8	Lung Injury 01/2018 - 10/2011
7	Glioma (Gliomas) 02/2022 - 02/2002
7	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2021 - 01/2014
7	Metaplasia 01/2021 - 03/2011
6	Hypertension (High Blood Pressure) 05/2022 - 08/2017
6	Body Weight (Weight, Body) 01/2022 - 03/2002
6	Hypersensitivity (Allergy) 12/2021 - 01/2005
6	Autoimmune Diseases (Autoimmune Disease) 12/2021 - 01/2002
6	Type 2 Diabetes Mellitus (MODY) 03/2021 - 01/2017
6	Idiopathic Pulmonary Fibrosis 01/2021 - 04/2013
6	Reperfusion Injury 07/2006 - 04/2000
5	Atherosclerosis 01/2022 - 01/2017
5	Adenocarcinoma of Lung 01/2021 - 01/2014
5	Obesity 12/2020 - 08/2012
5	Asthma (Bronchial Asthma) 10/2020 - 06/2014
5	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 01/2018 - 02/2012
5	Acute Lung Injury 02/2015 - 04/2011
5	Ischemia 02/2005 - 04/2000
4	Virus Diseases (Viral Diseases) 07/2022 - 01/2017
4	Hypoxia (Hypoxemia) 03/2022 - 11/2016
4	Wounds and Injuries (Trauma) 03/2022 - 03/2016
4	Cardiovascular Diseases (Cardiovascular Disease) 12/2021 - 07/2016
4	COVID-19 11/2021 - 01/2021
4	Chronic Disease (Chronic Diseases) 04/2021 - 07/2016
4	Metabolic Diseases (Metabolic Disease) 03/2021 - 01/2018
4	Cardiomegaly (Heart Hypertrophy) 02/2021 - 09/2013
4	Sepsis (Septicemia) 01/2020 - 12/2011
4	Pneumonia (Pneumonitis) 11/2019 - 08/2012
4	Colonic Neoplasms (Colon Cancer) 01/2019 - 04/2008
4	Insulin Resistance 11/2018 - 01/2016
4	Ventilator-Induced Lung Injury 01/2018 - 12/2011
4	Sarcoidosis (Schaumann Disease) 01/2017 - 01/2012
4	Pulmonary Fibrosis (Fibrosing Alveolitis) 12/2015 - 08/2012
4	Nephritis 04/2013 - 01/2009
3	Diarrhea 01/2022 - 01/2021
3	Chronic Obstructive Pulmonary Disease (COPD) 01/2022 - 09/2007
3	Pulmonary Hypertension 01/2022 - 01/2016
3	Edema (Dropsy) 12/2021 - 07/2006

Drug/Important Bio-Agent (IBA)

38	Proteins (Proteins, Gene)FDA Link 02/2022 - 01/2002
30	Biomarkers (Surrogate Marker)IBA 12/2021 - 04/2011
21	MicroRNAs (MicroRNA)IBA 01/2022 - 04/2011
20	Monoclonal AntibodiesIBA 12/2015 - 04/2000
16	tigatuzumabIBA 01/2019 - 09/2003
12	RNA (Ribonucleic Acid)IBA 01/2022 - 02/2007
12	TNF-Related Apoptosis-Inducing Ligand ReceptorsIBA 01/2021 - 04/2006
12	Death Domain ReceptorsIBA 01/2020 - 08/2002
11	Biological ProductsIBA 01/2022 - 01/2002
11	LigandsIBA 01/2021 - 02/2002
11	DC-specific ICAM-3 grabbing nonintegrin (DC-SIGN)IBA 01/2020 - 08/2006
10	Messenger RNA (mRNA)IBA 02/2021 - 01/2007
10	Small Interfering RNA (siRNA)IBA 01/2021 - 08/2009
10	P-SelectinIBA 01/2018 - 04/2000
9	AntioxidantsIBA 01/2022 - 08/2013
8	CytokinesIBA 01/2022 - 07/2003
8	Pharmaceutical PreparationsIBA 01/2021 - 08/2006
8	Protein Isoforms (Isoforms)IBA 01/2018 - 01/2014
7	Therapeutic UsesIBA 03/2022 - 01/2011
7	sphingosine 1-phosphate (sphingosine-1-phosphate)IBA 01/2020 - 10/2011
6	CollagenIBA 03/2022 - 04/2002
6	EnzymesIBA 01/2022 - 07/2013
6	AntibodiesIBA 01/2022 - 04/2003
6	Glucose (Dextrose)FDA LinkGeneric 03/2021 - 04/2012
6	Myosin-Light-Chain KinaseIBA 01/2018 - 01/2014
6	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2017 - 02/2002
6	Epidermal Growth Factor (EGF)IBA 01/2015 - 12/2003
5	Tyrosine Kinase InhibitorsIBA 10/2022 - 01/2016
5	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2022 - 01/2016
5	Phosphotransferases (Kinase)IBA 01/2022 - 02/2007
5	AutoantibodiesIBA 01/2021 - 04/2002
5	Antineoplastic Agents (Antineoplastics)IBA 01/2017 - 06/2014
5	Doxorubicin (Adriamycin)FDA LinkGeneric 02/2016 - 09/2003
5	Bleomycin (Blenoxane)FDA LinkGeneric 12/2015 - 01/2005
5	LectinsIBA 01/2015 - 12/2003
4	HydrogelsIBA 09/2022 - 01/2021
4	LipidsIBA 01/2022 - 01/2018
4	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2022 - 05/2017
4	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 09/2003
4	ErbB Receptors (EGF Receptor)IBA 01/2021 - 01/2016
4	ORALIT (ORS)IBA 01/2019 - 03/2011
4	Calmodulin (Calcium-Dependent Activator Protein)IBA 01/2017 - 09/2015
4	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 03/2016 - 11/2004
4	Basigin (Extracellular Matrix Metalloproteinase Inducer (EMMPRIN))IBA 10/2015 - 08/2011
4	Cisplatin (Platino)FDA LinkGeneric 10/2015 - 04/2006
4	Benzalkonium Compounds (Benzalkonium Chloride)FDA LinkGeneric 08/2014 - 01/2011
3	CreatinineIBA 06/2022 - 07/2006
3	Indicators and Reagents (Reagents)IBA 04/2021 - 09/2007

Therapy/Procedure

41	Therapeutics 05/2022 - 08/2002
14	Drug Therapy (Chemotherapy) 05/2022 - 04/2003
8	Radiotherapy 01/2022 - 09/2003